Rosetrees Frontiers of Medicine podcasts now available!

Check out our new podcasts on the latest news in medical research. Head over to the link: https://podcasters.spotify.com/pod/show/rosetrees-frontiers-of-me Hear about: advances in immunotherapy to fight cancer; genetic predictors of whether sufferers of benign prostatic hyperplasia will need surgery; is it possible to rescue lost brain connection in people with Alzheimer’s Disease?

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New study reveals molecular causes of rare neurological condition in children

A new study led by Rosetrees-funded scientists at UCL Queen Square Institute of Neurology has identified the molecular defects underlying a complex developmental brain condition in children. The researchers investigated the role of a specific regulatory protein in the brain known as acyl-CoA-binding domain-containing protein 6, or ACBD6. Up until now, the implication of defects…

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Rosetrees intermediate and major project grant round now open!

Rosetrees is delighted to invite applications for project grants across the whole spectrum of bio-medical research. However, we are particularly (though not exclusively) interested in projects that address unmet clinical needs in the areas of mental health, eczema, pain, sleep and infertility. As we have a fixed global budget to cover all the projects, applications…

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Stem cell-derived model of the post-implantation human embryo

Researchers at the University of Cambridge and in the U.S. have created an embryo-like model from human stem cells to better understand post-implantation embryo development. This 3D structure derived from pluripotent stem cells replicates some developmental processes that occur in early human embryos. With this model, researchers can now probe key questions of human post-implantation…

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Genetic Clues Reveal Lung Cancer’s Next Move

   Knowing whether a tumour might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that. In a series of seven papers published today (Weds April 12) in Nature and Nature Medicine, Cancer Research…

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The Riddle of Cachexia

Scientists examining the causes of cachexia – the sudden loss of weight, appetite, and muscle that some cancer patients experience in the later stages of the disease – believe they are now one step closer to understanding the causes behind the condition. The study, part of the Cancer Research UK TRACERx programme, and published in…

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New study reveals how skin cancer resists treatment

Scientists have discovered how some skin cancers stop responding to treatment at the end of life. An in-depth analysis of 14 patients who died from incurable melanoma has revealed that changes to the order, structure and number of copies of tumour DNA could cause some skin cancers to resist treatment. These changes also explain how…

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VIRTUAL REALITY TRANSFORMS EDI TRAINING

Chelsea and Westminster Hospital NHS Foundation Trust has successfully used virtual reality (VR) technology for the first time to provide immersive learning experiences for staff in equality, diversity and inclusion training. The pilot project, in partnership with leading VR company Kiin,  has shown overwhelmingly positive results, with 97% of participants saying they would recommend the…

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Creating complex protocells and prototissues using simple DNA building blocks

Rosetrees-funded researchers at UCL have utilized macromolecular DNA nanotechnology to build modular and predictable synthetic skeletal filaments inside and outside protocells and prototissues. these findings expand the boundaries of synthetic biology by enabling complex exo- and cytoskeletal structures to be fabricated in a simple, rapid, and predictable fashion. The cytoskeletal texture, stiffness, composition, and proximity…

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