Posts by Vineeth

A new study led by Rosetrees-funded scientists at UCL Queen Square Institute of Neurology has identified the molecular defects underlying a complex developmental brain condition in children. The researchers investigated the role of a specific regulatory protein in the brain known as acyl-CoA-binding domain-containing protein 6, or ACBD6. Up until now, the implication of defects…

Rosetrees is delighted to invite applications for project grants across the whole spectrum of bio-medical research. However, we are particularly (though not exclusively) interested in projects that address unmet clinical needs in the areas of mental health, eczema, pain, sleep and infertility. As we have a fixed global budget to cover all the projects, applications…

Researchers at the University of Cambridge and in the U.S. have created an embryo-like model from human stem cells to better understand post-implantation embryo development. This 3D structure derived from pluripotent stem cells replicates some developmental processes that occur in early human embryos. With this model, researchers can now probe key questions of human post-implantation…

Scientists led by UCL Queen Square Institute of Neurology have detailed how a combination of grafted replacement motor neurons and optical nerve stimulation – using light to activate neurons – can improve muscle function in a highly aggressive mouse model of ALS. Their research in mice, published as an eLife Reviewed Preprint, provides convincing evidence…

   Knowing whether a tumour might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that. In a series of seven papers published today (Weds April 12) in Nature and Nature Medicine, Cancer Research…

Scientists examining the causes of cachexia – the sudden loss of weight, appetite, and muscle that some cancer patients experience in the later stages of the disease – believe they are now one step closer to understanding the causes behind the condition. The study, part of the Cancer Research UK TRACERx programme, and published in…

Scientists have discovered how some skin cancers stop responding to treatment at the end of life. An in-depth analysis of 14 patients who died from incurable melanoma has revealed that changes to the order, structure and number of copies of tumour DNA could cause some skin cancers to resist treatment. These changes also explain how…

Chelsea and Westminster Hospital NHS Foundation Trust has successfully used virtual reality (VR) technology for the first time to provide immersive learning experiences for staff in equality, diversity and inclusion training. The pilot project, in partnership with leading VR company Kiin,  has shown overwhelmingly positive results, with 97% of participants saying they would recommend the…

Rosetrees-funded researchers at UCL have utilized macromolecular DNA nanotechnology to build modular and predictable synthetic skeletal filaments inside and outside protocells and prototissues. these findings expand the boundaries of synthetic biology by enabling complex exo- and cytoskeletal structures to be fabricated in a simple, rapid, and predictable fashion. The cytoskeletal texture, stiffness, composition, and proximity…

We are devastated to hear of Bruce Willis’ Frontotemporal Dementia diagnosis and send our thoughts and best wishes to him and his family during this challenging time. We thank him and his family for being so open and raising awareness of this rare dementia and it has been incredible to see all the love and…